Integration of sweet taste and metabolism determines carbohydrate reward - study 1

Non-caloric beverages were mixed from novel flavors, citric acid, sucralose and food coloring. For each session participants arrived to the lab fasted (4 hours). In the pre-conditioning session, participants were trained on how to use the scales to rate overall intensity, sweetness, liking, and wanting. Then participants rated each of the non-caloric stimuli 3 times. Average ratings were calculated and participants who rated 5 beverages as equally liked were asked to perform a triangle test to determine if they were able to reliably detect the presence of maltodextrin (DE = 12.5) in a beverage. Participants, with 5 similarly liked beverages who were unable to detect maltodextrin were then trained on the fMRI procedures. Meanwhile a second experimenter prepared the subject-specific beverage assignments so that color, flavors and caloric load were counterbalanced across subjects. The participant was then scheduled for 5 exposure sessions during which each beverage was consumed 6 times. Following the exposure sessions, subjects returned for a post-conditioning session where they rated the 10 non-caloric beverages for sweetness, liking, familiarity and wanting (as in the pre-conditioning session). An fMRI session followed in which participants sampled the non-caloric versions of the 5 exposed beverage (CS-, CS37.5, CS75, CS112.5, and CS150), as well as a tasteless and odorless control solution.

Tasks:

001 Gustatory stimulation with liquid tastes or flavors

Investigators:

  • Maria Geraldine Veldhuizen
  • Richard Keith Babbs
  • Barkha Patel
  • Wambura Fobbs
  • Nils B Kroemer
  • Elizabeth Garcia
  • Martin Yeomans
  • Dana M Small

Contact Information:

Name: Maria Veldhuizen
Email: mveldhuizen@jbpierce.org

Sample Size:

15

Scanner Type:

Siemens Trio Tim Syngo MR B17

License:

PDDL

Accession Number:

ds000229

How to cite this dataset:

In addition to any citation requirements in the dataset summary please use the following to cite this dataset:

This data was obtained from the OpenfMRI database. Its accession number is ds000229

Curated:

Yes

Browse Data For All Revisions on S3

Direct Links to data:

Revision: 1.0.0 Date Set: July 17, 2017, 10:53 p.m.

Notes:

- Initial Release