Integration of sweet taste and metabolism determines carbohydrate reward - study 1
Non-caloric beverages were mixed from novel flavors, citric acid, sucralose and food coloring. For each session participants arrived to the lab fasted (4 hours). In the pre-conditioning session, participants were trained on how to use the scales to rate overall intensity, sweetness, liking, and wanting. Then participants rated each of the non-caloric stimuli 3 times. Average ratings were calculated and participants who rated 5 beverages as equally liked were asked to perform a triangle test to determine if they were able to reliably detect the presence of maltodextrin (DE = 12.5) in a beverage. Participants, with 5 similarly liked beverages who were unable to detect maltodextrin were then trained on the fMRI procedures. Meanwhile a second experimenter prepared the subject-specific beverage assignments so that color, flavors and caloric load were counterbalanced across subjects. The participant was then scheduled for 5 exposure sessions during which each beverage was consumed 6 times. Following the exposure sessions, subjects returned for a post-conditioning session where they rated the 10 non-caloric beverages for sweetness, liking, familiarity and wanting (as in the pre-conditioning session). An fMRI session followed in which participants sampled the non-caloric versions of the 5 exposed beverage (CS-, CS37.5, CS75, CS112.5, and CS150), as well as a tasteless and odorless control solution.
Tasks:
001 Gustatory stimulation with liquid tastes or flavors
Investigators:
- Dana M Small
- Martin Yeomans
- Elizabeth Garcia
- Nils B Kroemer
- Wambura Fobbs
- Barkha Patel
- Richard Keith Babbs
- Maria Geraldine Veldhuizen
Contact Information:
Name: Maria VeldhuizenEmail: mveldhuizen@jbpierce.org
Sample Size:
15
Scanner Type:
Siemens Trio Tim Syngo MR B17
License:
Accession Number:
ds000229
How to cite this dataset:
In addition to any citation requirements in the dataset summary please use the following to cite this dataset:
This data was obtained from the OpenfMRI database. Its accession number is ds000229
Curated:
Yes
Browse Data For All Revisions on S3
Direct Links to data:
Revision: 1.0.0 Date Set: July 17, 2017, 10:53 p.m.
Notes:
- Initial Release