Learning and memory: motor skill consolidation and intermanual transfer

Participants were scanned during the performance of a finger-to-thumb opposition sequence (5-element), intensively trained a day earlier, and a similarly constructed, but novel, untrained sequence, using either their trained (left) or untrained hand. The imaging session consisted of 3 consecutive runs for each sequence and hand: Th – trained (left) hand, Uh – untrained (right) hand, T – trained sequence, U – untrained sequence. Experimental runs (each 144 seconds long) were separated by a 1.5 – 2 minutes break that included a verbal interaction with the participant. Each run consisted of two performance blocks (8 repetitions of a sequence paced by an auditory signal at a fixed rate of 1.66 Hz, during 24 sec each) separated by a rest interval of 30 seconds. Each run began and ended with a rest period of 36 seconds and 24 seconds, respectively.

Functional magnetic resonance imaging (fMRI) scanning was carried out at the C. Sheba Medical Center, Tel-Hashomer, using a 3 Tesla whole body high definition system (GE EXCITE 3 HD) equipped with an 8-channel head coil. A high-resolution full-brain 3D structural images were acquired in the axial orientation using a T1*-weighted echo-planar sequence (TR = 7.3 ms, TE = 3 ms, flip angle = 20°, FOV = 256 x 256 mm2, matrix size = 256 x 256 voxels, voxel size = 1 x 1 x 1 mm3). BOLD-sensitive functional images were obtained using a gradient echo-planar T2*-sequence (TR = 3000 ms, TE = 35 ms, flip angle=90°, FOV = 220 x 220 mm2, matrix size = 64 x 64 voxels, voxel size = 3.4 x 3.4 x 3.4 mm3, no gap, ascending) with 40 axial oblique slices, covering the whole brain.

Dataset contains: BOLD contrast fMRI and high resolution T1-weighted structural images.

Tasks:

001

Investigators:

  • Ella Gabitov
  • David Manor
  • Avi Karni

Acknowledgements and Funding:

E.G. was partially supported by a fellowship from the E. J. Safra Brain Research Center for the Study of Learning Disabilities. The research leading to these results has received funding from the European Union Seventh Framework Program (FP7/2007-2013) under grant agreement no. 604102 (Human Brain Project). We thank Tammi Kushnir, Ph.D., director of research at the C. Sheba Medical Center, for her technical and administrative support.

External Publication Links:

Learning from the other limb's experience: sharing the 'trained' M1 representation of the motor sequence knowledge.
Patterns of modulation in the activity and connectivity of motor cortex during the repeated generation of movement sequences.
Done that: short-term repetition related modulations of motor cortex activity as a stable signature for overnight motor memory consolidation.

Sample Size:

15

Scanner Type:

A 3 Tesla whole body high definition system (GE EXCITE 3 HD) equipped with an 8-channel head coil.

License:

PDDL

Accession Number:

ds000170

How to cite this dataset:

In addition to any citation requirements in the dataset summary please use the following to cite this dataset:

This data was obtained from the OpenfMRI database. Its accession number is ds000170

Curated:

Yes

Browse Data For All Revisions on S3

Direct Links to data:

Revision: 1.0.1 Date Set: April 16, 2016, 3:01 a.m.

Notes:

Added *_events.tsv files containing the onsets, durations, and condition names for the fMRI task. These were previously omitted due to an error in the curation process. For those interested in downloading only the event onsets file, it is included separately (as a single file) in the Links section. No changes were made to any of the other imaging data files.

Revision: 1.0.0 Date Set: Feb. 25, 2016, 4:41 p.m.

Notes:

Initial Release